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Kidney stones and kidney transplant

Do patients with kidney stones who receive kidney transplants fare worse than those without a history of kidney stones who undergo transplantation? 🤔

According to data from the Australia and New Zealand Transplant Registry (ANZDATA) involving 78,705 adult patients, including 22,869 who started kidney replacement therapy between January 1981 and December 2020, the outcomes may surprise you. 

The study revealed that there was no significant difference in mortality or graft loss between kidney stone formers and non-kidney stone formers who underwent kidney transplantation. However, patients with kidney stones experienced a longer time to transplant compared to non-kidney stone patients (2.5 vs 1.7 years, p 0.001). 

Interestingly, survival rates were higher among kidney stone formers who were on dialysis compared to non-kidney stone formers. This finding aligns with existing experience suggesting that patients with kidney stones who progress to kidney failure and require dialysis or transplantation tend to have better outcomes than those with other common causes of kidney failure like diabetes or glomerulonephritis.

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